Primary Hyperparathyroidism

A Comprehensive Study of Clinical, Biochemical and Radiographic Manifestations1
Published Online:

Clinical manifestations, radiographic findings, and bone mineral measurements of 65 patients with primary hyperparathyroidism are reviewed. Fifty per cent presented with renal stones, and 38% had asymptomatic hypercalcemia. Advanced hyperparathyroid skeletal disease was not encountered. On conventional skeletal survey, 10% had minimal subperiosteal bone resorption limited to the phalanges. Radiographically visible osteopenia was uncommon and difficult to assess. By absorptometric analysis and fine-detail radiography, a majority were found to have demineralization and excessive bone resorption. These results illustrate the limitations of conventional radiography and underscore the need for newer more sensitive radiological techniques.

Article History

Published in print: Dec 1973