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Cinematic Rendering of Neurofibromatosis Type I Gastrointestinal Stromal Tumors

Published Online:https://doi.org/10.1148/radiol.2019190104

A 56-year-old man with a history of neurofibromatosis type I and prior small bowel resection for gastrointestinal stromal tumor (GIST) presented for routine follow-up evaluation of multiple additional known small bowel GISTs. The patient was asymptomatic at the time of imaging. GISTs are uncommon tumors, although they are found in association with neurofibromatosis type I. Cinematic rendering is a novel three-dimensional visualization technique that uses a complex global lighting model to produce photorealistic images from standard CT acquisition volumetric data.

Figure a:

Figure a: (a) Coronal cinematic rendered image from arterial phase of intravenous contrast material–enhanced CT angiography demonstrates multiple avidly enhancing small bowel gastrointestinal stromal tumors (GISTs) (white arrows) and superficial skin neurofibromas (black arrows). (b) Coronal cinematic rendered image from same CT angiography examination better demonstrates the numerous small bowel GISTs (arrows).

Figure b:

Figure b: (a) Coronal cinematic rendered image from arterial phase of intravenous contrast material–enhanced CT angiography demonstrates multiple avidly enhancing small bowel gastrointestinal stromal tumors (GISTs) (white arrows) and superficial skin neurofibromas (black arrows). (b) Coronal cinematic rendered image from same CT angiography examination better demonstrates the numerous small bowel GISTs (arrows).

Disclosures of Conflicts of Interest: S.P.R. Activities related to the present article: disclosed no relevant relationships. Activities not related to the present article: institution received research funding from Progenics Pharmaceuticals and Mitoluminate. Other relationships: disclosed no relevant relationships. E.K.F. Activities related to the present article: disclosed no relevant relationships. Activities not related to the present article: is cofounder of HipGraphics; institution receives grant support from Siemens Healthcare and GE Healthcare. Other relationships: disclosed no relevant relationships.

Article History

Received: Jan 14 2019
Accepted: Feb 11 2019
Published online: Mar 19 2019
Published in print: May 2019