Is Gadolinium-based Contrast Material Needed for MRI Follow-up of Multiple Sclerosis?

References

• 1. Simon JH, Li D, Traboulsee A, et al. Standardized MR imaging protocol for multiple sclerosis: Consortium of MS Centers consensus guidelines. AJNR Am J Neuroradiol 2006;27(2):455–461.
  Medline Google Scholar
• 2. Miller DH, Barkhof F, Nauta JJ. Gadolinium enhancement increases the sensitivity of MRI in detecting disease activity in multiple sclerosis. Brain 1993;116(Pt 5): 1077–1094.
  Medline Google Scholar
• 3. Gulani V, Calamante F, Shellock FG, Kanal E, Reeder SB; International Society for Magnetic Resonance in Medicine. Gadolinium deposition in the brain: summary of evidence and recommendations. Lancet Neurol 2017;16(7):564–570.
  Medline Google Scholar
• 4. Murata N, Murata K, Gonzalez-Cuyar LF, Maravilla KR. Gadolinium tissue deposition in brain and bone. Magn Reson Imaging 2016;34(10):1359–1365.
  Medline Google Scholar
• 5. Eichinger P, Schon S, Pongratz V, et al. Accuracy of unenhanced MRI in the detection of new brain lesions in multiple sclerosis. Radiology 2019;291:429–435.
  Google Scholar
• 6. Mattay RR, Davtyan K, Bilello M, Mamourian AC. Do all patients with multiple sclerosis benefit from the use of contrast on serial follow-up MR imaging? A retrospective analysis. AJNR Am J Neuroradiol 2018;39(11):2001–2006.
  Medline Google Scholar
• 7. Cotton F, Weiner HL, Jolesz FA, Guttmann CR. MRI contrast uptake in new lesions in relapsing-remitting MS followed at weekly intervals. Neurology 2003;60(4): 640–646.
  Medline Google Scholar