Improved Image Quality and Detection of Acute Cerebral Infarction with PROPELLER Diffusion-weighted MR Imaging

PURPOSE: To compare periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) multishot fast spin-echo diffusion-weighted magnetic resonance (MR) imaging with single-shot echo-planar diffusion-weighted MR imaging for image quality and visualization of acute cerebral infarction.

MATERIALS AND METHODS: Seventy subjects (35 men, 35 women; mean age, 55 years ± 24 [SD]) who were suspected of having acute cerebral infarction (symptom duration, 2.8 days ± 2.7) underwent PROPELLER and echo-planar MR imaging (b = 1,000 sec/mm2). Two neuroradiologists compared unlabeled images for presence of artifacts, visualization of infarction, and their preference of images. Interobserver agreement and image comparison were assessed by using the κ statistic and the χ2 test, respectively.

RESULTS: PROPELLER MR imaging reduced susceptibility artifacts (n = 70 subjects), which limited visualization of temporal (echo-planar, n = 64; PROPELLER, n = 0; P < .01, χ2 test), frontal (echo-planar, n = 58; PROPELLER, n = 1; P < .01), and parietal lobes (echo-planar, n = 5; PROPELLER, n = 0; P < .05) and cerebellum (echo-planar, n = 36; PROPELLER, n = 0; P < .01) and brainstem (echo-planar, n = 23; PROPELLER, n = 0; P < .01). Acute infarction (n = 31 subjects) was better demonstrated at PROPELLER MR imaging (PROPELLER better, n = 18; echo-planar better, n = 1; PROPELLER and echo-planar equal, n = 12; P < .01, χ2 test). PROPELLER MR imaging was preferred in all (n = 70) but one case in which the lesion lay within the intersection gap (PROPELLER preferred, n = 69; echo-planar preferred, n = 1; P < .01, χ2 test).

CONCLUSION: With a short increase in imaging time, PROPELLER MR imaging offers better image quality and detection of acute cerebral infarction than does echo-planar MR imaging.

© RSNA, 2002


  • 1 van Everdingen KJ, van der Grond J, Kappelle LJ, et al. Diffusion-weighted magnetic resonance imaging in acute stroke. Stroke 1998; 29:1783-1790. Crossref, MedlineGoogle Scholar
  • 2 Moseley ME, Kucharczyk J, Mintorovitch J, et al. Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats. AJNR Am J Neuroradiol 1990; 11:423-429. MedlineGoogle Scholar
  • 3 Turner R, Le Bihan D, Maier J, et al. Echo-planar imaging of intravoxel incoherent motion. Radiology 1990; 177:407-414. LinkGoogle Scholar
  • 4 Ojemann JG, Akbudak E, Snyder AZ, et al. Anatomic localization and quantitative analysis of gradient refocused echo-planar fMRI susceptibility artifacts. Neuroimage 1997; 6:156-167. Crossref, MedlineGoogle Scholar
  • 5 Pipe JG. Motion correction with PROPELLER MRI: application to head motion and free-breathing cardiac imaging. Magn Reson Med 1999; 42:963-969. Crossref, MedlineGoogle Scholar
  • 6 Forbes KP, Pipe JG, Bird CR, Heiserman JE. PROPELLER MRI: clinical testing of a novel technique for quantification and compensation of head motion. J Magn Reson Imaging 2001; 14:215-222. Crossref, MedlineGoogle Scholar
  • 7 Pipe JG. Multishot diffusion weighted FSE with PROPELLER. Magn Reson Med 2002; 47:42-52. Crossref, MedlineGoogle Scholar
  • 8 Lissac M, Metrop D, Brugirard J, et al. Dental materials and magnetic resonance imaging. Invest Radiol 1991; 26:40-45. Crossref, MedlineGoogle Scholar
  • 9 Shellock FG, Kanal E. Aneurysm clips: evaluation of MR imaging artifacts at 1.5 T. Radiology 1998; 209:563-566. LinkGoogle Scholar

Article History

Published in print: Nov 2002