Guidelines for Management of Small Pulmonary Nodules Detected on CT Scans: A Statement from the Fleischner Society

References

• 1 OstD, Fein AM, Feinsilver SH. The solitary pulmonary nodule. N Engl J Med2003;348:2535–2542.
  Medline Google Scholar
• 2 TanBB, Flaherty KR, Kazerooni EA, Iannettoni MD; American College of Chest Physicians. The solitary pulmonary nodule. Chest2003;123(suppl 1):89S–96S.
  Medline Google Scholar
• 3 SwensenSJ, Silverstein MD, Ilstrup DM, Schleck CD, Edell ES. The probability of malignancy in solitary pulmonary nodules: application to small radiologically indeterminate nodules. Arch Intern Med1997;157:849–855.
  Medline Google Scholar
• 4 MidthunDE, Swensen SJ, Jett JR, Hartman TE. Evaluation of nodules detected by screening for lung cancer with low dose spiral computed tomography. Lung Cancer2003;41(suppl 2):S40.
  Google Scholar
• 5 HenschkeCI, Yankelevitz DF, Naidich DP, et al. CT screening for lung cancer: suspiciousness of nodules according to size on baseline scans. Radiology2004;231(1):164–168.
  Google Scholar
• 6 AberleDR, Gamsu G, Henschke CI, Naidich DP, Swensen SJ. A consensus statement of the Society of Thoracic Radiology: screening for lung cancer with helical computed tomography. J Thorac Imaging2001;16(1):65–68.
  Medline Google Scholar
• 7 SwensenSJ, Jett JR, Hartman T, et al. Screening for lung cancer with CT: Mayo Clinic experience. Radiology2003;226(3):756–761.
  Google Scholar
• 8 HenschkeCI, Naidich DP, Yankelevitz DF, et al. Early Lung Cancer Action Project: initial findings on repeat screening. Cancer2001;92:153–159.
  Medline Google Scholar
• 9 HenschkeCI, McCauley DI, Yankelevitz D, et al. Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancet1999;354:99–105.
  Medline Google Scholar
• 10 BrennerDJ. Radiation risks potentially associated with low-dose CT screening of adult smokers for lung cancer. Radiology2004;231(2):440–444.
  Google Scholar
• 11 MayoJR, Alrich J, Müller NL. Radiation exposure at chest CT: a statement of the Fleischner Society. Radiology2003;228(1):15–21.
  Google Scholar
• 12 ImhofH, Schibany N, Ba-Ssalamah A, et al. Spiral CT and radiation dose. Eur J Radiol2003;47(1):29–37.
  Medline Google Scholar
• 13 KalraMK, Maher MM, Toth TL, et al. Strategies for CT radiation dose optimization. Radiology2004;230(3):619–628.
  Google Scholar
• 14 BenjaminMS, Drucker EA, McLoud T, Shepard JO. Small pulmonary nodules: detection at chest CT and outcome. Radiology2003;226(2):489–493.
  Google Scholar
• 15 RevelMP, Lefort C, Bissery A, et al. Pulmonary nodules: preliminary experience with three-dimensional evaluation. Radiology2004;231(2):459–466.
  Google Scholar
• 16 RevelMP, Bissery A, Bienvenu M, Aycard L, Lefort C, Frija G. Are two-dimensional CT measurements of small noncalcified pulmonary nodules reliable? Radiology2004;231(2):453–458.
  Google Scholar
• 17 YankelevitzDF, Gupta R, Zhao B, Henschke CI. Small pulmonary nodules: evaluation with repeat CT—preliminary experience. Radiology1999;212:561–566.
  Google Scholar
• 18 KostisW, Yankelevitz DF, Reeves AP, Fluture SC, Henschke CI. Small pulmonary nodules: reproducibility of three-dimensional volumetric measurement and estimation of time to follow-up CT. Radiology2004;231(2):446–452.
  Google Scholar
• 19 HasegawaM, Sone S, Takashima S, et al. Growth rate of small lung cancers detected on mass CT screening. Br J Radiol2000;73:1252–1259.
  Medline Google Scholar
• 20 UsudaK, Sato Y, Sagawa M, et al. Tumor doubling time and prognostic assessment of patients with primary lung cancer. Cancer1994;74(8):2239–2244.
  Medline Google Scholar
• 21 Winer-MuramHT, Jennings SG, Tarver RD, et al. Volumetric growth rate of stage I lung cancer prior to treatment: serial CT scanning. Radiology2002;223(3):798–805.
  Google Scholar
• 22 SoneS, Li F, Yang ZG, et al. Results of three-year mass screening programme for lung cancer using mobile low-dose spiral computed tomography scanner. Br J Cancer2001;84(1):25–32.
  Medline Google Scholar
• 23 Cancer statistics in Japan '99: index of tables—standardized cancer mortality ratio among daily smokers in Japan (cohort study 1966-1982). National Cancer Center Web site. http://www.ncc.go.jp/en/statistics/1999/tables.html. Updated December 1, 2004.
  Google Scholar
• 24 HirayamaT. Non-smoking wives of heavy smokers have a higher risk of lung cancer: a study from Japan. Br Med J (Clin Res Ed)1981;282(6259):183–185.
  Medline Google Scholar
• 25 U.S. Department of Health and Human Services. The health consequences of smoking: a report of the surgeon general. Atlanta, Ga: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 1982.
  Google Scholar
• 26 GuyattGH, Newhouse MD. Are active and passive smoking harmful? determination of causation. Chest1985;88(3):445–451.
  Medline Google Scholar
• 27 RischHA, Howe G, Jain M, Burch JD, Holowaty EJ, Miller AB. Are female smokers at higher risk for lung cancer than male smokers? a case-control analysis by histologic type. Am J Epidemiol1993;138(5):281–293.
  Medline Google Scholar
• 28 BlotWJ, McLaughlin JK. Are women more susceptible to lung cancer? J Natl Cancer Inst2004;96(11):812–813.
  Medline Google Scholar
• 29 ZangEA, Wynder EL. Differences in lung cancer risk between men and women: examination of the evidence. J Natl Cancer Inst1996;88:183–192.
  Medline Google Scholar
• 30 BainC, Feskanich D, Speizer FE, et al. Lung cancer rates in men and women with comparable histories of smoking. J Natl Cancer Inst2004;96:826–834.
  Medline Google Scholar
• 31 MayneST, Buenconsejo J, Janerich D. Familial cancer history and lung cancer risk in United States nonsmoking men and women. Cancer Epidemiol Biomarkers Prev1999;8:1065–1069.
  Medline Google Scholar
• 32 Bailey-WilsonJE, Amos CI, Pinney SM, et al. A major lung cancer susceptibility locus maps to chromosome 6q2325. Am J Hum Genet2004;75:460–474.
  Medline Google Scholar
• 33 LeePN. Relation between exposure to asbestos and smoking jointly and the risk of lung cancer. Occup Environ Med2001;58:145–153.
  Medline Google Scholar
• 34 GottliebLS, Husen LA. Lung cancer among Navajo uranium miners. Chest1982;81:449–452.
  Medline Google Scholar
• 35 FieldRW, Steck DJ, Smith BJ, et al. Residential radon gas exposure and lung cancer: the Iowa Radon Lung Cancer Study. Am J Epidemiol2000;151(11):1091–1102.
  Medline Google Scholar
• 36 SwensenSJ. CT. Screening for lung cancer. AJR Am J Roentgenol2002;179:833–836.
  Medline Google Scholar
• 37 PastorinoU, Bellomi M, Landoni C, et al. Early lung-cancer detection with spiral CT and positron emission tomography in heavy smokers: 2-year results. Lancet2003;362:593–597.
  Medline Google Scholar
• 38 BachPB, Kattan M, Thornquist MD, et al. Variations in lung cancer risk among smokers. J Natl Cancer Inst2003;95(6):470–478.
  Medline Google Scholar
• 39 HenschkeCI, Yankelevitz DF, Mirtcheva R, et al. CT screening for lung cancer: frequency and significance of part-solid and nonsolid nodules. AJR Am J Roentgenol2002;178:1053–1057.
  Medline Google Scholar
• 40 AokiT, Nakata H, Watanabe H, et al. Evolution of peripheral lung adenocarcinomas: CT findings correlated with histology and tumor doubling time. AJR Am J Roentgenol2000;174:763–768.
  Medline Google Scholar
• 41 LiF, Sone S, Abe H, MacMahon H, Doi K. Comparison of thin section CT findings in malignant and benign nodules in CT screening for lung cancer. Radiology2004;233(3):793–798.
  Google Scholar
• 42 GadgeelSM, Ramalingam S, Cummings G, Kraut MJ, Wozniak AJ, Gaspar LE. Lung cancer in patients < 50 years of age: the experience of an academic multidisciplinary program. Chest 1999;115(5):1232–1236.
  Medline Google Scholar
• 43 SwensenSJ, Viggiano RW, Midthun DE, et al. Lung nodule enhancement at CT: multicenter study. Radiology2000;214:73–80.
  Google Scholar
• 44 RohrenEM, Turkington TG, Coleman RE. Clinical applications of PET in oncology. Radiology2004;231(2):305–332.
  Google Scholar
• 45 YamagamiT, Iida S, Kato T, Tanaka O, Nishimura T. Combining fine-needle aspiration and core biopsy under CT fluoroscopy guidance: a better way to treat patients with lung nodules? AJR Am J Roentgenol2003;180:811–815.
  Medline Google Scholar
• 46 SuzukiK, Nagai K, Yoshida J, et al. Video-assisted thoracoscopic surgery for small indeterminate pulmonary nodules. Chest1999;115:563–568.
  Medline Google Scholar
• 47 AustinJH, Müller N, Friedman PJ, et al. Glossary of terms for CT of the lungs: recommendations of the nomenclature committee of the Fleischner Society. Radiology1996;200:327–331.
  Google Scholar
• 48 TakashimaS, Sone S, Li F, et al. Small solitary pulmonary nodules (≤1 cm) detected at population-based CT screening for lung cancer: reliable high-resolution CT features of benign lesions. AJR Am J Roentgenol2003;180:955–964.
  Medline Google Scholar
• 49 ErasmusJJ, Connolly JE, McAdams HP, Roggli VL. Solitary pulmonary nodules. I. Morphologic evaluation for differentiation of benign and malignant lesions. RadioGraphics2000;20:43–58.
  Google Scholar
• 50 GaerteSC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ. Fat-containing lesions of the chest. RadioGraphics2002;22(Spec Issue):S61–S78.
  Google Scholar
• 51 WangJC, Sone S, Feng L, et al. Rapidly growing small peripheral lung cancers detected by screening CT: correlation between radiological appearance and pathological features. Br J Radiol2000;73:930–937.
  Medline Google Scholar
• 52 TakashimaS, Sone S, Li F, Maruyama Y, Hasegawa M, Kadoya M. Indeterminate solitary pulmonary nodules revealed at populations-based CT screening of the lung: using first follow-up diagnostic CT to differentiate benign and malignant lesions. AJR Am J Roentgenol2003;180:1255–1263.
  Medline Google Scholar
• 53 HeitzmanER, Markarian B, Raasch BN, et al. Pathways of tumor spread through the lung: radiologic correlations with anatomy and pathology. Radiology1982;144(1):3–14.
  Google Scholar
• 54 YanoM, Arai T, Inagaki K, Morita T, Nomura T, Ito H. Intrapulmonary satellite nodule of lung cancer as a T factor. Chest1998;114:1305–1308.
  Medline Google Scholar
• 55 ByersTE, Vena JE, Rzepka TF. Predilection of lung cancer for the upper lobes: an epidemiologic inquiry. J Natl Cancer Inst1984;72:1271–1275.
  Medline Google Scholar
• 56 HyodoT, Kanazawa S, Dendo S, et al. Intrapulmonary lymph nodes: thin-section CT findings, pathological findings, and CT differential diagnosis from pulmonary metastatic nodules. Acta Med Okayama2004;58(5):235–240.
  Medline Google Scholar
• 57 QuintLE, Park CH, Iannettoni MD. Solitary pulmonary nodules in patients with extrapulmonary neoplasms. Radiology2000;217:257–261.
  Google Scholar
• 58 ReadWL, Tierney RM, Page NC, et al. Differential prognostic impact of comorbidity. J Clin Oncol2004;22:3099–3103.
  Medline Google Scholar
• 59 BerlinL. Malpractice issues in radiology: failure to diagnose lung cancer—anatomy of a malpractice trial. AJR Am J Roentgenol2003;180:37–45.
  Medline Google Scholar