Vascular and Interventional Radiology

Secondary Postpartum Hemorrhage: Treatment with Selective Arterial Embolization

PURPOSE: To evaluate the efficacy and safety of selective arterial embolization of the uterine arteries in the management of intractable delayed postpartum hemorrhage.

MATERIALS AND METHODS: Fourteen consecutive women with secondary postpartum hemorrhage were treated with selective embolization of the uterine arteries. In all cases, hemostatic embolization was performed because of intractable hemorrhage that could not be controlled with the administration of uterotonic drugs or with uterine curettage.

RESULTS: The causes of bleeding included genital tract tears in four women and endometritis in eight women; the endometritis was associated with proved, retained portions of placenta in four women. In two women, no evident cause of bleeding was found before angiography. Angiography revealed extravasation in three women. A false aneurysm of the uterine artery was found in two women. In one patient, an arteriovenous fistula was observed. Immediate resolution of external bleeding was observed in all women. No complication related to embolization was found. Normal menstruation resumed in all women.

CONCLUSION: Selective arterial embolization of the uterine arteries is a safe and effective means of controlling secondary postpartum hemorrhage.

References

  • 1 Gilbert L, Porter W, Brown VA. Postpartum haemorrhage: a continuing problem. Br J Obstet Gynaecol 1987; 94:67-71. Crossref, MedlineGoogle Scholar
  • 2 Gilstrap LC, III, Ramin SM. Postpartum hemorrhage. Clin Obstet Gynecol 1994; 37:824-830. Crossref, MedlineGoogle Scholar
  • 3 Herbert WP, Cefalo RC. Management of postpartum hemorrhage. Clin Obstet Gynecol 1984; 27:139-147. Crossref, MedlineGoogle Scholar
  • 4 King PA, Duthie SJ, Dong ZG, Ma HK. Secondary postpartum haemorrhage. Aust N Z J Obstet Gynecol 1989; 29:394-398. Crossref, MedlineGoogle Scholar
  • 5 Rome RM. Secondary postpartum hemorrhage. Br J Obstet Gynaecol 1975; 82:289-292. Crossref, MedlineGoogle Scholar
  • 6 Ghares EE, Albert SN, Dodek SM. Intrapartum blood loss measured with Cr 51-tagged erythrocytes. Obstet Gynecol 1962; 19:455-462. MedlineGoogle Scholar
  • 7 Newton M, Mosey LM, Egli GE, Gifford WB, Hull CT. Blood loss during and immediately after delivery. Obstet Gynecol 1961; 17:9-18. MedlineGoogle Scholar
  • 8 Combs CA, Murphy EL, Laros RK, Jr. Factors associated with postpartum hemorrhage with vaginal birth. Obstet Gynecol 1991; 77:69-76. MedlineGoogle Scholar
  • 9 Combs CA, Murphy EL, Laros RK, Jr. Factors associated with hemorrhage in cesarean deliveries. Obstet Gynecol 1991; 77:77-82. MedlineGoogle Scholar
  • 10 Strickland DM, Galey WT, Hauth JC. Hypofibrinogenemia as a cause of delayed postpartum hemorrhage. Am J Obstet Gynecol 1982; 143:230-231. Crossref, MedlineGoogle Scholar
  • 11 Ojomo EO, Ezimokhai M, Reale FR, Nwabineli NJ. Recurrent postpartum hemorrhage caused by endometrial carcinoma co-existing with endometrioid carcinoma of the ovary in a full term pregnancy. Br J Obstet Gynaecol 1993; 100:489-491. Crossref, MedlineGoogle Scholar
  • 12 Sergent F, Clavier E, Rachet B, Marpeau L. Late post-partum hemorrhage after cesarean section due to rupture of a false aneurysm of the uterine pedicle. J Gynecol Obstet Biol Reprod 1997; 26:641-644[French]. MedlineGoogle Scholar
  • 13 Ramin KD, Ramin SM, Webb LS, Radford LR, Sewall LE. Antepartum diagnosis of pelvic arteriovenous malformation. Obstet Gynecol 1996; 88:647-650. Crossref, MedlineGoogle Scholar
  • 14 Evans S, McShane P. The efficacy of internal iliac artery ligation in obstetric hemorrhage. Surg Gynecol Obstet 1985; 160:250-253. MedlineGoogle Scholar
  • 15 Clark SL, Yeh SY, Phelan JP, Bruce S, Paul RH. Emergency hysterectomy for obstetric hemorrhage. Obstet Gynecol 1984; 64:376-380. MedlineGoogle Scholar
  • 16 Burchell RC. Physiology of internal iliac artery ligation. J Obstet Gynaecol Br Commonwealth 1968; 75:642-651. Crossref, MedlineGoogle Scholar
  • 17 Ring EJ, Athanasoulis C, Waltman AC, Margolies MN, Baum S. Arteriographic management of hemorrhage following pelvic fractures. Radiology 1973; 109:65-70. LinkGoogle Scholar
  • 18 Goldstein HM, Medellin H, Ben-Menachem Y, Wallace S. Transcatheter arterial embolization in the management of bleeding in the cancer patient. Radiology 1975; 115:603-608. LinkGoogle Scholar
  • 19 Greenwood LH, Glickman MG, Schwartz PE, Morse SS, Denny DF. Obstetric and nonmalignant gynecologic bleeding: treatment with angiographic embolization. Radiology 1987; 164:155-159. LinkGoogle Scholar
  • 20 Lang EK. Transcatheter embolization of pelvic vessels for control of intractable hemorrhage. Radiology 1981; 140:331-339. LinkGoogle Scholar
  • 21 Markoff G, Quagliarello J, Rosen RJ, Beckman EM. Uterine arteriovenous malformation successfully embolized with a liquid polymer, isobutyl 2-cyanoacrylate. Am J Obstet Gynecol 1986; 155:659-660. Crossref, MedlineGoogle Scholar
  • 22 Rosenthal DM, Colapinto R. Angiographic arterial embolisation in the management of postoperative vaginal hemorrhage. Am J Obstet Gynecol 1985; 151:227-231. Crossref, MedlineGoogle Scholar
  • 23 Haseltine FP, Glickman MG, Marchesi S, Spitz R, Dlugi A, DeCheney AA. Uterine embolization in a patient with postabortal hemorrhage. Obstet Gynecol 1984; 63(3 suppl):78-80. Google Scholar
  • 24 Chin HG, Scott DR, Resnik R, et al. Angiographic embolization of intractable puerperal hematomas. Am J Obstet Gynecol 1989; 160:434-438. Crossref, MedlineGoogle Scholar
  • 25 Mitty HA, Sterling KM, Alvarez M, Gendler R. Obstetric hemorrhage: prophylactic and emergency arterial catheterization and embolotherapy. Radiology 1993; 188:183-187. LinkGoogle Scholar
  • 26 Yamashita Y, Takahashi M, Ito M, Okumura H. Transcatheter arterial embolization in the management of postpartum hemorrhage due to genital tract injury. Obstet Gynecol 1991; 77:160-163. MedlineGoogle Scholar
  • 27 Brown BJ, Heaston DK, Poulson AM, Gabert HA, Mineau DE, Miller FJ, Jr. Uncontrollable postpartum bleeding: a new approach to hemostasis through angiographic arterial embolization. Obstet Gynecol 1979; 54:361-365. MedlineGoogle Scholar
  • 28 Yamashita Y, Harada M, Yamamoto H, et al. Transcatheter arterial embolization of obstetric and gynaecological bleeding: efficacy and clinical outcome. Br J Radiol 1994; 67:530-534. Crossref, MedlineGoogle Scholar
  • 29 Collins CD, Jackson JE. Pelvic arterial embolization following hysterectomy and bilateral internal iliac artery ligation for intractable primary post partum haemorrhage. Clin Radiol 1995; 50:710-714. Crossref, MedlineGoogle Scholar
  • 30 Sproule MW, Bendomir AM, Grant KA, Reid AW. Embolisation of massive bleeding following hysterectomy, despite internal iliac artery ligation. Br J Obstet Gynaecol 1994; 101:908-909. Crossref, MedlineGoogle Scholar
  • 31 Chait A, Moltz A, Nelson JH, Jr. The collateral arterial circulation in the pelvis: an angiographic study. AJR 1968; 102:392-400. CrossrefGoogle Scholar
  • 32 Hare WSC, Holland CJ. Paresis following internal iliac artery embolization. Radiology 1983; 146:47-51. LinkGoogle Scholar
  • 33 Sieber PR. Bladder necrosis secondary to pelvic artery embolization: case report and literature review. J Urol 1994; 151:422. Crossref, MedlineGoogle Scholar
  • 34 Behnam K, Jarmolowski CR. Vesicovaginal fistula following hypogastric embolization for control of intractable pelvic hemorrhage. J Reprod Med 1982; 27:304-306. MedlineGoogle Scholar
  • 35 Mengert WF, Burchell RC, Blumstein RW, Daskal JL. Pregnancy after bilateral ligation of the internal iliac and ovarian arteries. Obstet Gynecol 1969; 34:664-666. MedlineGoogle Scholar
  • 36 Stancato-Pasik A, Mitty HA, Richard HM, III, Eshkar N. Obstetric embolotherapy: effect on menses and pregnancy. Radiology 1997; 204:791-793. LinkGoogle Scholar

Article History

Published in print: Aug 1999