Mechanisms of Uptake of Common Radiopharmaceuticals RadioGraphics Fundamentals | Online Presentation
Abstract
Classifying radiopharmaceuticals by their mechanisms of uptake helps radiologists accurately interpret nuclear medicine images by facilitating an understanding of the physiologic distributions and the potential for creating false negatives and false positives.
Suggested Readings
- . Cardiac neurotransmission imaging. J Nucl Med 2001;42(7):1062–1076.
- . Cloning and characterization of the thyroid iodide transporter. Nature 1996;379(6564): 458–460.
- . Indium-111-labeled leukocytes for the detection of infection: current status. Semin Nucl Med 1994;24(2): 92–109.
- . Somatostatin receptors in gastroentero-pancreatic neuroendocrine tumours. Endocr Relat Cancer 2003;10(4): 451–458.
- Renal handling of technetium-99m DMSA: evidence for glomerular filtration and peritubular uptake. J Nucl Med 1989;30(7):1219–1223.
- . Iodine-131 metaiodobenzylguanidine therapy for neuroblastoma: reports so far and future perspective. Sci World J 2015;2015:189135.
- . Thallium 201 scintigraphy. West J Med. 1980;133(1):26-43.
- . Essentials of nuclear medicine imaging. 5th ed. Philadelphia, PA: Elsevier, 2006.
- . The retention mechanism of technetium-99m-HM-PAO: intracellular reaction with glutathione. J Cereb Blood Flow Metab 1988;8(6):S4–S12.
- . Mechanism of accumulation of 99mTc-MDP to bone: correlation of in vivo data with in vitro data. Radiat Med 1997;15(4):209–215.
- . Mathematical simulation of transport kinetics of tumor-imaging radiopharmaceutical 99mTc-MIBI. Comput Math Methods Med 2017;2017:2414878.
- . PET/CT today and tomorrow. J Nucl Med 2004;45(suppl 1):4S–14S.
- . Pharmacokinetics of (99m)Tc-MAG3. AJR Am J Roentgenol 2009;193(4):W361; author reply W362.
Article History
Received: Mar 11 2018Revision requested: May 4 2018
Revision received: June 1 2018
Accepted: June 10 2018
Published online: Sept 12 2018
Published in print: Sept 2018








