Table of Contents

Understanding the imaging and clinical features of hepatocellular adenomas and their unique genotypic subtypes is important in the detection, characterization, and monitoring of these tumors.

RadLex is a key RSNA initiative that provides shared terminology and a shared domain model to facilitate the integration of radiology informatics resources in clinical care, quality improvement, research, and education.

Zoonotic infections pose a diagnostic challenge because of their nonspecific clinical manifestations and the need for specialized testing procedures to confirm these diagnoses.

Mesotheliomas and benign mesothelial lesions demonstrate characteristic pathomolecular findings and cross-sectional imaging features with varied biologic behavior and prognosis, and imaging plays a pivotal role in diagnosis, staging, assessing surgical resectability, and evaluating treatment response.

Paraneoplastic syndromes are rare conditions associated with underlying malignancies that can involve diverse organ systems, and awareness of the relevant imaging features can facilitate early diagnosis and treatment.

Evaluating the distribution and imaging findings of lymph node metastases from an unknown primary site is important for radiologists to identify the primary tumor and help determine the correct diagnosis and optimal treatment.

Determining the likelihood of immunoglobulin G4–related disease (IgG4-RD) by means of histopathologic, serologic, and radiologic findings may prevent unnecessary surgical resection, as IgG4-RD responds well to medical therapy.

Fluorine 18 fluoroestradiol (FES) PET/CT is approved in the United States as an adjunct to biopsy in patients with recurrent or metastatic ER-positive breast cancer and can be used to select target lesions for confirmatory biopsies, assess the overall burden of functionally ER-positive metastatic breast cancer, clarify FDG-avid findings, and assess ER expression heterogeneity.

Pediatric midfacial fractures have patterns similar to those in adults, but the relative incidence of fracture patterns and associated complications change as the patient’s skeletal development progresses from infant to adolescent.

The decision to offer radiation therapy after mastectomy for breast cancer is controversial in some cases, and these cases are often presented for multidisciplinary tumor board discussions in which radiologists play a pivotal role.

Understanding the O-RADS US lexicon and how to apply it accurately can improve care in daily practice by decreasing unnecessary follow-up and surgery and promoting rapid referral to a gynecologic oncologist.

The role of interventional radiology in women’s health has expanded significantly in the past few years, with new clinical applications necessitating recognition of new patient categorization and treatment algorithms and adaptation of existing treatments for conditions affecting women.